| Event | Time | Athlete | Year, Meet |
| 50 Freestyle | 22.46 | Sara Li | 2013, Ivy League Championships |
| 100 Freestyle | 48.67 | Sara Li | 2013, ECAC Championships |
| 200 Freestyle | 1:45.88 | Sara Li | 2013, Ivy League Championships |
| 500 Freestyle | 4:42.84 | Alexandra Clarke | 2009, Ivy League Championships |
| 1,000 Freestyle | 9:43.09 | Alexandra Clarke | 2009, Ivy League Championships |
| 1,650 Freestyle | 16:10.25 | Alexandra Clarke | 2010, NCAA Championships |
| 50 Backstroke | 25.15 | Kendall Crawford | 2013, Ivy League Championships |
| 100 Backstroke | 53.59 | Kendall Crawford | 2013, HYP |
| 200 Backstroke | 1:54.94 | Meghan Leddy | 2011, Georgia Invitational |
| 100 Breaststroke | 1:02.33 | Mackenzie Luick | 2013, Ivy League Championships |
| 200 Breaststroke | 2:13.90 | Jaclyn Pangilinan | 2005, NCAA Championships |
| 100 Butterfly | 53.79 | Kendall Crawford | 2013, HYP |
| 200 Butterfly | 1:56.23 | Kate Mills | 2009, Ivy League Championships |
| 200 Individual Medley | 2:00.31 | Courtney Otto | 2012, Georgia Invitational |
| 400 Individual Medley | 4:10.22 | Courtney Otto | 2012, Ivy League Championships |
| 200 Freestyle Relay | 1:32.40 | Katy Hinkle, Ali Slack, Sara Li, Jenna Gregoire |
2011, Ivy League Championships |
| 400 Freestyle Relay | 3:20.32 |
Katy Hinkle, Sara Li, |
2011, Ivy League Championships |
| 800 Freestyle Relay | 7:13.71 |
Alexandra Clarke, Katherine Pickard, |
2009, Ivy League Championships |
| 200 Medley Relay | 1:39.48 |
Kendall Crawford, Mackenzie Luick, |
2013, Ivy League Championships |
| 400 Medley Relay | 3:38.21 |
Kendall Crawford, Mackenzie Luick, |
2013, Ivy League Championships |
| 1-Meter Diving (dual) | 324.15 | Jenny Greene | 1987, Eastern Championships |
| 1-Meter Diving (championship) | 486.90 | Jenny Greene | 1988, Eastern Championships |
| 3-Meter Diving (dual) | 356.48 | Samantha Papadakis | 2007, vs. New Hampshire |
| 3-Meter Diving (championship) | 519.20 | Brittany Garza | 2000, Harvard Diving Invitational |